Sensei Biotherapeutics Announces Nature Communications Publication Describing Mechanism of Action of SNS-101 Selectively Targeting the Active Form of VISTA within the Tumor Microenvironmen...
Sensei Biotherapeutics, Inc. (SNSE)
Company Research
Source: Yahoo! Finance
discovery and development of next-generation therapeutics for cancer patients, today announced the publication of a peer-reviewed research paper in Nature Communications. The research was conducted by scientists at Sensei Biotherapeutics in collaboration with genOway and the laboratory of Dr. Robert Schreiber at the Washington University, St. Louis School of Medicine. The paper describes Sensei Biotherapeutics' approach to the discovery and development of SNS-101, which was designed to potently and selectively target the active protonated form of VISTA, a protein that plays a significant role in suppressing T-cell activation. VISTA was previously considered undruggable due to its extensive expression on myeloid cells, leading to safety issues such as cytokine release syndrome (CRS), in addition to a pharmacokinetic sink, which poses a significant challenge in reaching therapeutically relevant concentrations. The paper details the mechanism and characteristics of SNS-101, a novel pH-
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News
- Sensei Biotherapeutics to Present Topline Clinical Data from the SNS-101 Phase I Dose Escalation Study at the 2024 ASCO Annual MeetingGlobeNewswire
- Sensei Biotherapeutics to Participate in Canaccord Genuity’s Horizons in Oncology Virtual ConferenceGlobeNewswire
- Sensei Biotherapeutics Announces Nature Communications Publication Describing Mechanism of Action of SNS-101 Selectively Targeting the Active Form of VISTA within the Tumor MicroenvironmentGlobeNewswire
- Sensei Biotherapeutics to Participate in the 3rd Annual VISTA SymposiumGlobeNewswire
- Sensei Biotherapeutics to Present New Preclinical Data at Upcoming Scientific Conferences [Yahoo! Finance]Yahoo! Finance
SNSE
Earnings
- 8/3/23 - Beat
SNSE
Sec Filings
- 4/29/24 - Form ARS
- 4/29/24 - Form DEFA14A
- 4/29/24 - Form DEF
- SNSE's page on the SEC website