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0.000209643605869979 0.000209643605869979 0.000209643605869979 0.000838574423480066 -0.00524109014675052 -0.00587002096436061 -0.00429769392033539 -0.00922431865828087
Stock impact report

AstraZeneca stock jumps after surprise trial win for lung disease drug where rivals have failed [MSNBC.com]

Sanofi - American Depositary Shares (SNY) 
US:NYSE Investor Relations: sanofi.com/en/investors
Company Research Source: MSNBC.com
In this articleAstraZenecaThe respiratory treatment tozorakimab, reduced flare-ups of chronic obstructive pulmonary disease (COPD) in both former smokers and in the overall population versus placebo, the company said."This marks a notable shift in sentiment, given limited conviction in the IL-33 mechanism following prior IL-33 failures fromSanofiRocheTozorakimab and rival drugs belong to a class of treatments called monoclonal antibodies. They work ?by suppressing the action ?of the protein interleukin-33 (IL-33) and can reduce inflammation."Today's tozorakimab results deliver the first two confirmatory Phase III trials for an IL-33 biologic, which is a major scientific advancement in COPD, the world's third leading cause of death," said Sharon Barr, executive vice president of biopharmaceuticals and R&D at AstraZeneca."Tozorakimab works in a fundamentally different way from other biologics, inhibiting the signalling of the reduced and oxidised forms of IL-33 to both decrease inflamma Show less Read more
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