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0.000320102432778501 0.000320102432778501 0.000213401621852435 0.000213401621852435 0.000213401621852435 0.001280409731114 -0.00149381135296629 -0.000853606487409286
Stock impact report

Sanofi eczema drug weighed down by mixed results, safety concerns [Yahoo! Finance]

Sanofi - American Depositary Shares (SNY) 
US:NYSE Investor Relations: sanofi.com/en/investors
Company Research Source: Yahoo! Finance
Dive Brief: Sanofi disappointed some on Wall Street with its latest look at an experimental eczema drug that the French pharmaceutical giant has pegged as a potential blockbuster. On Saturday, Sanofi said the drug, amlitelimab, met the primary endpoints of two late-stage studies titled COAST 1 and COAST 2. These experiments tested amlitelimab by itself, across two different dosing regimens, in patients aged 12 and older who have moderate-to-severe atopic dermatitis. After 24 weeks of treatment, amlitelimab met the main goals of both trials — which, for the U.S. and other countries where similar regulatory expectations apply, focused on the proportion of patients whose skin was deemed “clear” or “almost clear” and had improved by at least two points on a five-point scale researchers use to assess the severity of eczema. However, COAST 2 did not meet statistical significance on co-primary endpoints meant for the for the European Union and its reference countries. A third trial du Show less Read more
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