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Stock impact report

First Advanced Oral Treatment For Asthma - Sanofi's Investigational Drug Shows Potential [Yahoo! Finance]

Sanofi - American Depositary Shares (SNY) 
US:NYSE Investor Relations: sanofi.com/en/investors
Company Research Source: Yahoo! Finance
Two doses of rilzabrutinib, 800 mg daily and 1200 mg daily, were studied. The data showed that treatment with oral rilzabrutinib at both high and low doses led to a numerical reduction in loss of asthma control (LOAC) events (the primary endpoint) and improvements in symptoms in adult patients with uncontrolled moderate-to-severe asthma. These results were presented at the 2024 American Thoracic Society (ATS) International Conference in San Diego and will support the phase 3 program, in which a twice-daily dose of rilzabrutinib will be studied for moderate-to-severe asthma. In this proof-of-concept study, treatment with high and low doses of rilzabrutinib resulted in a 36% and 25% relative risk reduction in loss of asthma control (LOAC) events, respectively, at week 12 (primary endpoint). Significant and clinically meaningful improvements in asthma symptoms were also observed with a -0.54/-0.59 LS mean difference in the asthma control questionnaire. Rilzabrutinib high and l Show less Read more
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