Recludix Pharma Announces Dosing of First Subjects in a Phase 1 Study of REX-8756, a Potent and Selective Oral STAT6 Inhibitor, and Achieves Associated $20 Million Milestone Payment Under ...
Sanofi - American Depositary Shares (SNY)
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Company Research
Source: Yahoo! Finance
--In preclinical studies, REX-8756 elicited complete, rapid and durable inhibition of STAT6, resulting in potent, biologic-like activity without protein degradation in models of inflammatory diseases --Several healthy volunteers have already received REX-8756, triggering a milestone payment of $20 million to Recludix under the collaboration with Sanofi SAN DIEGO, Jan. 12, 2026 (GLOBE NEWSWIRE) -- Recludix Pharma, a clinical-stage company leading the discovery and development of inhibitors of challenging targets for inflammatory disease, today announced it has begun dosing healthy volunteers in a Phase 1 study of REX-8756 (also known as SAR448755), an oral, small molecule STAT6 inhibitor that has demonstrated compelling efficacy and safety in preclinical models of different types of inflammatory diseases based on selective and complete STAT6 inhibition. The achievement of this milestone triggered a payment of $20 million to Recludix under the collaboration agreement with Sanofi.
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