Spectrum Pharmaceuticals Provides Strategy Update for Poziotinib Development Program
Spectrum Pharmaceuticals, Inc. (SPPI)
Last spectrum pharmaceuticals, inc. earnings: 2/27 04:00 pm
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Source: Business Wire
ZENITH20 Phase 2 clinical trial amended to include new dosing regimens aimed at improving therapeutic indexManagement to host webcast and conference call today to review data and program strategy at 8:30 a.m. ET HENDERSON, Nev.--(BUSINESS WIRE)--Spectrum Pharmaceuticals (NasdaqGS: SPPI), a biopharmaceutical company focused on novel and targeted oncology therapies, today provided an update on its ZENITH20 Phase 2 clinical trial evaluating poziotinib in non-small cell lung cancer (NSCLC) patients with EGFR and HER2 exon 20 insertion mutations. The protocol has been amended to explore additional twice daily dosing regimens as well as lower single daily dosage amounts. Earlier use of corticosteroids has also been added to the protocol in an effort to help patients better tolerate poziotinib and stay on therapy for a longer time. Previously announced results for Cohort 1 of the SPECTRUM20 trial were presented yesterday during the oral plenary of the Lung Cancer Targeted Therapy session
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