TriSalus Life Sciences’ Pressure-Enabled Drug Delivery (PEDD) Significantly Increased Therapeutic Effect of Anti-CEA CAR-T in Pancreatic Cancer Patients with Liver Metastases
Sorrento Therapeutics, Inc. (SRNE)
Last sorrento therapeutics, inc. earnings: 8/9 04:49 pm
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Source: Business Wire
PEDD overpowers intratumoral high pressure, significantly increasing CAR-T into solid tumors Median overall survival (OS) 8.3 months and mean OS 9.8 months vs. 3 to 6 months standard of care Two of four stage IV patients who failed systemic chemotherapy showed metabolic complete response (CR); no visible liver metastases on PET WASHINGTON--(BUSINESS WIRE)-- A phase 1b clinical trial shows that administering a concentrated dose of anti-CEA CAR-T cells precisely at the site of a solid tumor by means of TriSalus™ Life Sciences’ unique Pressure-enabled Drug Delivery (PEDD) is safe, with encouraging clinical responses. The preliminary Hepatic Immunotherapy for Metastases (HITM-SURE) clinical trial results will be presented in a poster at the Society for Immunotherapy of Cancer (SITC) Annual Meeting, being held November 7-11 in Washington, DC. A separate
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