Stemline Therapeutics Recaps Felezonexor (SL-801) Clinical Data Presentation From ESMO 2019 Congress
STEMLINE THERAPEUTICS (STML)
Last stemline therapeutics earnings: 3/13 04:45 pm
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Source: GlobeNewswire
NEW YORK, Oct. 01, 2019 (GLOBE NEWSWIRE) -- Stemline Therapeutics, Inc. (Nasdaq: STML), a commercial-stage biopharmaceutical company focused on the development and commercialization of novel oncology therapeutics, presented updated clinical data on the felezonexor (SL-801) Phase 1 trial in patients with advanced solid tumors at the European Society of Medical Oncology (ESMO) 2019 Annual Congress in Barcelona, Spain. The presentation is now available on the Stemline website, www.stemline.com, under the Scientific Presentations tab. Felezonexor is a novel, oral, small molecule that reversibly inhibits Exportin-1 (XPO1), a nuclear export protein, overexpressed in a variety of solid and hematologic malignancies. XPO1 is a mediator of nuclear-cytoplasmic transport of nuclear proteins and has been associated with aggressive tumor behavior and poor prognosis. XPO1 is a clinically validated target in oncology, and the FDA recently approved an XPO1 inhibitor drug, in combination with other
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