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Onconova Therapeutics Announces Positive Preclinical Data for Third-Generation Oral CDK4/6 + ARK5 Inhibitor and dual FLT3 and Src inhibitor at 2017 American Association of Cancer Research...

Onconova Therapeutics, Inc. (ONTX) 
Last onconova therapeutics, inc. earnings: 11/12 05:10 pm Check Earnings Report
US:NASDAQ Investor Relations: investor.onconova.com/investor-overview
Company Research Source: GlobeNewswire
Comparative biological studies with PalbociclibSingle-agent activity of ON 123300 in various models including multiple myeloma and lymphoma NEWTOWN, Pa., April 04, 2017 (GLOBE NEWSWIRE) -- Onconova Therapeutics, Inc. (Nasdaq: ONTX), a Phase 3 stage biopharmaceutical company focused on discovering and developing small molecule drug candidates to treat cancer, with a primary focus on Myelodysplastic Syndromes, announced promising pre-clinical data for first-in-class dual inhibitor of CDK4/6 + ARK5, as well as a Type 1 novel inhibitor of FLT3 and Src pathways as a novel strategy for Acute Myeloid Leukemia (AML) therapy at the 2017 AACR Annual Meeting. The Company presented its findings in two poster presentations on April 3, 2017. ON 123300, an orally administered novel CDK4/6 + ARK5 inhibitor, exhibits potent antitumor activity in vivo: comparative studies with Palbociclib ON 123300, a third-generation potent CDK4/6 inhibitor that also inhibits ARK5 with low nanomolar potency, was Show less Read more
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