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Stock impact report

Onconova stays the course with late-stage study of rigosertib in MDS; shares up 13% [Seeking Alpha]

Onconova Therapeutics, Inc. (ONTX) 
Last onconova therapeutics, inc. earnings: 11/12 05:10 pm Check Earnings Report
US:NASDAQ Investor Relations: investor.onconova.com/investor-overview
Company Research Source: Seeking Alpha
Onconova stays the course with late-stage study of rigosertib in MDS; shares up 13%Thinly traded nano cap Onconova Therapeutics (ONTX+12.6%) is up on a healthy 36x surge in volume (although down almost 30% from the intraday high of $2.66) on the heels of itsannouncement that it will advance the Phase 3 INSPIRE study assessing lead candidate rigosertib in patients with treatment-resistant myelodysplastic syndromes (MDS).The company made its decision following an interim analysis by the independent Data Monitoring Committee. It remains blinded to the preliminary data.Rigosertib is a small molecule that inhibits cellular signaling by acting as aRas protein mimetic. Ras is a family of proteins that are involved in transmitting signals within cells. When switched "on", it activates other proteins that ultimately turn on genes involved in cell growth, differentiation and survival.Previously:Onconova up 18% on positive Phase 3 outlook on lead candidate rigosertib (Oct. 9, 2017)See all stocks Show less Read more
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