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Stock impact report

Ipsen outlays $1bn for China-based Simcere's preclinical ADC [Yahoo! Finance]

Sutro Biopharma, Inc. (STRO) 
Last sutro biopharma, inc. earnings: 11/8 07:00 am Check Earnings Report
Company Research Source: Yahoo! Finance
The French drugmaker has signed a licensing deal with Simcere Zaiming for SIM0613, an ADC asset due to start clinical development in 2026. The agreement sees Ipsen secure global rights for the cancer treatment outside of Greater China, with Simcere Zaiming eligible for upfront, development, regulatory and commercial milestone payments that could reach $1.06bn. Ipsen will have manufacturing rights, along with taking charge of Phase I preparation activities and submission of regulatory applications. The therapy has demonstrated “robust tumour regressions in multiple in vivo preclinical models”, according to Ipsen. The pharma company is eyeing the launch of a Phase I trial evaluating SIM0613 in cancer patients in the second half of 2026. SIM0613 targets the leucine-rich repeat-containing 15 (LRRC15), a protein highly expressed on various tumour types and cancer-associated fibroblasts but with limited expression on normal cells. Like other ADCs, the drug works in a targeted approach, Show less Read more
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