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Synlogic Announces Clinical Collaboration to Evaluate SYNB1891 in Combination with PD-L1 Checkpoint Inhibitor in Patients with Advanced Solid Tumors

Synlogic, Inc. (SYBX) 
Last synlogic, inc. earnings: 3/12 04:19 pm Check Earnings Report
Company Research Source: Business Wire
CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Synlogic, Inc., (Nasdaq: SYBX) a clinical stage company applying synthetic biology to beneficial microbes to develop novel, living medicines, today announced a new clinical collaboration with Roche (SIX:RO, ROG), to explore Synlogic’s Synthetic Biotic™ medicine, SYNB1891, a dual innate immune activator engineered to express a STING agonist, in combination with Roche’s PD-L1-blocking checkpoint inhibitor (CPI) atezolizumab (Tecentriq®) in patients with advanced solid tumors. Synlogic expects to file an Investigational New Drug (IND) application with the U.S. Federal Drug Administration (FDA) in the second half of 2019 for SYNB1891 to enable the company to begin an open-label Phase 1 clinical trial to evaluate the candidate as a monotherapy and a combination treatment with atezolizumab. “This collaboration is an important step in advancing SYNB1891 as a potential tr Show less Read more
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