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Stock impact report

Volunteers are swallowing E. coli bacteria pills to help medicine [The Business Insider]

Synlogic, Inc. (SYBX) 
Last synlogic, inc. earnings: 3/12 04:19 pm Check Earnings Report
Volunteers are swallowing E. coli bacteria pills to help medicine Shutterstock/science photo Somewhere in Baltimore, volunteers are gulping capsules filled with GMOs—gene-modified E. coli bacteria, to be precise. Synlogic of Cambridge, Massachusetts, the company behind the unusual study, is testing what it calls “ synthetic biotics ,” or bacteria engineered to carry out specialized jobs in a person’s stomach. Inside the pills are E. coli engineered to sop up ammonia inside the gut of people who can’t get rid of it fast enough. The study signals how genetic engineers are hoping to harness the microbiome , as the trillions of microscopic organisms that dwell within you are known. The drug is designed to help people suffering from disorders of the “urea cycle.” That’s the metabolic flywheel inside your liver that gets rid of excess nitrogen. For people whose urea cycles are faulty, excess nitrogen turns into ammonia, just like what’s under your kitchen sink, and just as hazardous. Th Show less Read more
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