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0.03115438108484 0 -0.0364394993045898 -0.0364394993045898 -0.0364394993045898 0.0406119610570237 0.0250347705146036 0.0141863699582753
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Spyre Therapeutics Announces Presentations at the 21st ECCO Congress Supporting Differentiated Profile of SPY003 and Novel Animal Studies Demonstrating Superiority of Combination Approach

Spyre Therapeutics, Inc. (SYRE) 
Company Research Source: GlobeNewswire
WALTHAM, Mass., Feb. 18, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases, today announced scientific presentations at the 21st Congress of the European Crohn’s and Colitis Organisation (ECCO), held February 18-21, 2026 in Stockholm, Sweden. “We are excited to share follow-up data out to 20 weeks from our Phase 1 study of SPY003, our potential best-in-class anti-IL-23 agent in development for IBD. The data showed SPY003 was well tolerated, had a differentiated PK profile supporting quarterly or twice-yearly dosing, and demonstrated targeted biological activity via a reduction in downstream cytokines. In addition, we are presenting details of our innovative SKYLINE platform trial evaluating long-acting antibodies as monotherapies and in rational combinations, as well as precl Show less Read more
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