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-0.0522774327122152 -0.0522774327122152 -0.0522774327122152 -0.0522774327122152 -0.00621118012422365 0.0119047619047619 0.0219979296066253 0.00569358178053827
Stock impact report

Updates To Syros Pharmaceuticals Thesis [Seeking Alpha]

Syros Pharmaceuticals, Inc. (SYRS) 
Last syros pharmaceuticals, inc. earnings: 3/5 06:57 am Check Earnings Report
US:NASDAQ Investor Relations: ir.syros.com
Company Research Source: Seeking Alpha
Summary Shares of Syros Pharmaceuticals (NASDAQ: SYRS ) have risen over 40% since I suggested that readers capitalize on this gene control first mover. SYRS data by YCharts One key to the investment thesis was the significant opportunity in AML and MDS being addressed, with the company's use of the RARA biomarker and SY-1425's prior approval in Japan (under the name Amnolake) slightly de-risking the mid-stage trial. Another was very strong preclinical data for SY-1365 highlighting the key role of CDK7 as a master regulator and showing how sensitive cancer cells are to the loss of CDK7's signals. Advancing SY-1365 Management announced that the first patient has been dosed in a phase 1 study in patients with advanced tumors. These include transcriptionally dependent settings such as triple negative breast, ovarian and small cell lung cancer. The trial will enroll 70 patients along with expansion cohorts exclusively recruiting patients with transcrip Show less Read more
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