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Protara Therapeutics Announces Dosing of First Patient in Phase 3 Registrational THRIVE-3 Trial of IV Choline Chloride in Patients on Long-Term Parenteral Support

Protara Therapeutics, Inc. (TARA) 
Company Research Source: GlobeNewswire
NEW YORK, Jan. 07, 2026 (GLOBE NEWSWIRE) -- Protara Therapeutics, Inc. (Nasdaq: TARA), a clinical-stage company developing transformative therapies for the treatment of cancer and rare diseases, today announced that patient dosing is now underway in its Phase 3 registrational THRIVE-3 clinical trial evaluating intravenous (IV) Choline Chloride in patients receiving long-term parenteral support (PS). IV Choline Chloride, the Company’s investigational phospholipid substrate replacement therapy, was previously granted Fast Track designation by the U.S. Food and Drug Administration. “Choline deficiency, which can lead to serious hepatic injury, neuropsychological impairment, muscle damage, and thrombotic abnormalities, has been shown to impact 78% of patients dependent on PS, yet there are currently no approved IV choline products globally to address this pressing need,” said Jesse Shefferman, Chief Executive Officer of Protara Therapeutics. “We believe that IV Choline Chloride has the Show less Read more
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