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Stock impact report

TG Therapeutics concludes enrolment in Phase III Briumvi trial [Yahoo! Finance]

TG Therapeutics, Inc. (TGTX) 
Last tg therapeutics, inc. earnings: 11/12 07:34 am Check Earnings Report
US:NASDAQ Investor Relations: ir.tgtherapeutics.com
Company Research Source: Yahoo! Finance
Currently approved in the US and selected regions outside the US, Briumvi is now given as a one-hour intravenous (IV) infusion biannually following the initial dose. The randomised, non-inferiority, parallel-group, multi-centre, open-label trial will compare the pharmacodynamics, pharmacokinetics, radiological, safety, and clinical outcomes of subcutaneous Briumvi with IV Briumvi among adults with RMS. Participants have been randomly assigned to receive either an every eight-week regimen or an every 12-week regimen of subcutaneous Briumvi, or the approved IV dosing schedule. The trial's primary endpoint is to demonstrate non-inferior drug exposure for subcutaneous Briumvi compared to IV administration, measured as area under the curve (AUC) at week 24. Briumvi is a monoclonal antibody that targets a specific epitope on cluster of differentiation 20 (CD20)-expressing B-cells. It is approved in the US for adults with RMS, and in the European Union and the UK for adults with a Show less Read more
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