Tiziana Life Sciences to Dose First Patient in Phase 2 Alzheimer’s Trial
Tiziana Life Sciences Ltd - Common Shares (TLSA)
Company Research
Source: GlobeNewswire
First Patient Expected to be Dosed Next Week with Intranasal ForalumabPET Scan Shows Presence of Untreated Neuroinflammation in Alzheimer’s Patient on Leqembi® (Lecanemab) Anti-Amyloid Therapy BOSTON, Dec. 12, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, announces that enrolment has begun in its Phase 2 randomized, placebo-controlled early Alzheimer’s clinical trial and plans to dose the first patient next week. The Phase 2 clinical trial will evaluate intranasal foralumab both as monotherapy and in combination with an FDA approved anti-amyloid therapy, lecanemab or donanemab, in patients with early Alzheimer’s disease (AD). Baseline clinical assessments, cognitive testing, TSPO-PET imaging, and fluid biomarkers have been completed in the first particip
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News
- Tiziana Life Sciences Announces Withdrawal of Proposed Public OfferingGlobeNewswire
- Tiziana Life Sciences to Dose First Patient in Phase 2 Alzheimer's Trial [Yahoo! Finance]Yahoo! Finance
- Tiziana Life Sciences Plans to Spinout IL-6 Asset into Separate Listed CompanyGlobeNewswire
- Tiziana Life Sciences Nasal Foralumab Phase 2 Clinical Trial Accepted into Healey ALS MyMatch ProgramGlobeNewswire
- Tiziana Life Sciences to Present at Jefferies Global Healthcare ConferenceGlobeNewswire
TLSA
Sec Filings
- 12/15/25 - Form 6-K
- 12/12/25 - Form 424B5
- 12/12/25 - Form FWP
- TLSA's page on the SEC website