resTORbio Announces Interim Results for Phase 1b/2a Trial of RTB101 in Patients with Parkinson’s Disease and Provides Corporate Update
RESTORBIO (TORC)
Last restorbio earnings: 3/12 07:30 am
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Source: GlobeNewswire
-- Interim data from three cohorts in the Phase 1b/2a study demonstrate that RTB101 is well tolerated, crosses the blood brain barrier, and reaches concentrations in cerebrospinal fluid observed in preclinical models to inhibit the activity of TORC1 and induce autophagy in neuronal cells -- -- TORC1 Inhibition in the brain with RTB101 may offer a new treatment paradigm for multiple neurodegenerative diseases associated with the accumulation of protein aggregates, such as Parkinson’s, Huntington’s and Alzheimer’s disease -- BOSTON, Feb. 19, 2020 (GLOBE NEWSWIRE) -- resTORbio (Nasdaq: TORC) today announced interim results from the ongoing Phase 1b/2a trial of RTB101, an orally-administered small molecule potent target of rapamycin complex 1 (TORC1) inhibitor product candidate, alone or in combination with sirolimus, in Parkinson’s disease (PD). “We are pleased to have observed that RTB101 is well tolerated and crosses the blood brain barrier in Parkinson’s disease patients at
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