Trillium Therapeutics Updates On Lead Lymphoma Trials [Seeking Alpha]
Trillium Therapeutics Inc. - Common Shares (TRIL)
Last trillium therapeutics inc. - common shares earnings: 5/13 07:00 am
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Source: Seeking Alpha
Summary Trillium Therapeutics ( TRIL ) is a Canadian biopharmaceutical company developing fusion-proteins targeting CD47, an immune checkpoint inhibitor involved in suppression of the innate immune system (macrophages). If you are new to the CD47 story, I recommend you start here . Last week, Trillium posted updated data from early phase trials of their lead compound, TTI-621, in various lymphoma subtypes. I previously wrote about TTI-621 and the CD47 pathway and will reserve this article for the discussion of Trillium's updated results. As a reminder, TRIL is evaluating TTI-621 in ongoing trials using two methods of delivery: Intravenous (IV) Intratumoral The lead trials for TTI-621 are in diffuse large B-cell lymphoma (DLBCL) and cutaneous T-cell lymphoma (CTCL), but Trillium is also exploring TTI-621 in a variety of other hematological malignancies. A brief background of Cutaneous T-Cell Lymphoma: Lymphomas arise as cancer of the lymphocytes (white
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