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Stock impact report

Taysha Gene Therapies Regains Full Global Rights to Lead Rett Syndrome Program TSHA-102 [Yahoo! Finance]

Taysha Gene Therapies, Inc. (TSHA) 
Company Research Source: Yahoo! Finance
announced that it had regained full global rights to its lead program, TSHA-102, which is in clinical evaluation for the treatment of Rett syndrome. The 2022 Option Agreement between Taysha and Astellas has officially expired. The agreement granted Astellas an exclusive option to negotiate an exclusive license to TSHA-102 for Rett syndrome. Taysha now holds unencumbered rights to the program, granting the company full strategic flexibility and optionality to drive long-term value. Taysha had delivered a TSHA-102 data package to Astellas in mid-2025, which contained the previously disclosed Part A REVEAL Phase 1/2 clinical data (with a May 2025 data cutoff). Taysha Gene Therapies Regains Full Global Rights to Lead Rett Syndrome Program TSHA-102 TSHA-102 is a self-complementary intrathecally delivered AAV9 investigational gene transfer therapy designed as a one-time treatment. It addresses the genetic root cause of Rett syndrome by delivering a functional form of the MECP2 gene to Show less Read more
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