Upstream Bio Presents Data Showing Structural and Mechanistic Drivers of Verekitug’s Potent Pharmacodynamic Activity and Differentiated Clinical Profile at European Respiratory Society Con...
Upstream Bio, Inc. (UPB)
Company Research
Source: GlobeNewswire
– Data show verekitug prevents TSLP binding to the TSLP receptor by occupying ligand binding sites – – Additionally, findings show that verekitug outcompetes TSLP in the presence of preformed heterodimeric receptor complexes – – Data support the potential of verekitug’s unique mechanism of action to achieve a differentiated therapeutic effect across a broad range of TSLP-driven severe respiratory diseases – WALTHAM, Mass., Sept. 30, 2025 (GLOBE NEWSWIRE) -- Upstream Bio, Inc. (Nasdaq: UPB), a clinical-stage company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders, today presented structural and mechanistic data showing verekitug’s potent pharmacodynamic activity through its unique approach of targeting the thymic stromal lymphopoietin (TSLP) receptor. Data were presented at the European Respiratory Society (ERS) Congress being held September 27 – October 1, 2025, in Amsterdam, Netherlands. “We continue to deepen our u
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UPB
News
- Upstream Bio (NASDAQ:UPB) is now covered by analysts at Lifesci Capital. They set an "outperform" rating and a $43.00 price target on the stock.MarketBeat
- Upstream Bio (UPB): Evaluating Valuation After 10% Share Price Surge [Yahoo! Finance]Yahoo! Finance
- Upstream Bio to Participate in Upcoming December Investor Conferences [Yahoo! Finance]Yahoo! Finance
- Upstream Bio to Participate in Upcoming December Investor ConferencesGlobeNewswire
- Upstream Bio Reports Third Quarter 2025 Financial Results and Highlights Continued ProgressGlobeNewswire
UPB
Sec Filings
- 11/14/25 - Form SCHEDULE
- 11/14/25 - Form SCHEDULE
- 11/5/25 - Form S-3ASR
- UPB's page on the SEC website