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Stock impact report

Circular RNA: Vaccines, therapeutics and biomarkers could be revolutionised [Yahoo! Finance]

Vertex Pharmaceuticals Incorporated (VRTX) 
Last vertex pharmaceuticals incorporated earnings: 4/29 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: investors.vrtx.com
Company Research Source: Yahoo! Finance
mRNA therapies and vaccines have revolutionised the drug development space in the last few years thanks to breakthroughs in advanced research. Now, only a few years after the first mRNA vaccine was authorised, the mRNA approach may soon be trumped by circular RNA (circRNA). CircRNA is a type of single-stranded RNA that, unlike linear RNA, forms a covalently closed continuous loop. In circular RNA, the 3' and 5' ends that are normally present in an RNA molecule are joined together. mRNA vaccines will be key in preventing and treating diseases in the future, but expensive manufacturing, requirements for cold-chain storage, and difficulties in transporting make their use complicated. In such circumstances, circRNA could step in and take its place. Alex Wesselhoeft, PhD, director of RNA Therapeutics at the Gene and Cell Therapy Institute, Mass General Brigham, says it is still early days with circRNA, but based on preclinical research, these candidates could be even better than mRN Show less Read more
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