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Stock impact report

Aadi Bioscience Conference: Whitehawk Unveils 3-Program ADC Pipeline, Targets First Data in 2027 [Yahoo! Finance]

Whitehawk Therapeutics, Inc. (WHWK) 
Company Research Source: Yahoo! Finance
million in cash at Q3 and says that funding should support operations into early 2028 , while targeting initial clinical readouts for its lead ADCs in the first half of 2027 (with the third program planned to start later). The company runs a three-program ADC platform built around a shared, deruxtecan-like topo-1 payload and licensed linker-payload system CPT-113 , using a DAR of 6 and claiming very high circulation stability (payload release ~ molar, or ~ 10x–100x more stable than typical ADCs) to boost tumor delivery and tolerability. Program highlights: HWK-007 (PTK7) is entering dose escalation and targets a widely expressed antigen (up to ~70% of tumors) with ~20–30 patients expected at readout; HWK-016 (MUC16) is engineered to bind below the CA-125 cleavage site to avoid an antigen sink and aims for high ORRs in gynecologic cancers; and HWK-206 (SEZ6) is a biparatopic ADC planned for IND/Phase 1 initiation in Q3. Interested in Aadi Bioscience, Inc.? Here are five stocks we Show less Read more
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