ZyVersa Therapeutics Announces Research Published in The Journal of Clinical Investigation Reinforcing IC 100’s Rationale for Inhibiting ASC Specks to Attenuate Spread of Inflammation into...
ZyVersa Therapeutics, Inc. (ZVSA)
Company Research
Source: GlobeNewswire
Patients with chronic kidney disease (“CKD”) exhibit chronic systemic inflammation characterized by increased circulating levels of IL-1ß, IL-6, and CRP.This study demonstrated that CKD-induced IL-1ß activates NLRP3 inflammasomes in the heart’s atria to trigger inflammation promoting the onset and progression of atrial fibrillation (“AF”). ZyVersa is developing Inflammasome ASC Inhibitor IC 100, designed to inhibit inflammasomes and their associated extracellular ASC specks to attenuate propagation of IL-1ß that triggers damaging inflammation and its spread to surrounding tissues. WESTON, Fla., Sept. 22, 2023 (GLOBE NEWSWIRE) -- ZyVersa Therapeutics, Inc. (Nasdaq: ZVSA, or “ZyVersa”), a clinical stage specialty biopharmaceutical company developing first-in-class drugs for treatment of inflammatory and renal diseases, announces publication of a paper in the peer-reviewed Journal of Clinical Investigation highlighting how inflammation in the kidneys can trigger inflammation in the h
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ZVSA
Sec Filings
- 12/3/25 - Form 8-K
- 11/19/25 - Form 8-K
- 11/19/25 - Form 10-Q
- ZVSA's page on the SEC website