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0.000184774575018441 9.23872875091547E-05 9.23872875091547E-05 0.000277161862527727 -0.000369549150037013 0.000369549150036881 -0.000369549150037013 -9.2387287509286E-05
Stock impact report

Hepta Unveils First Multi-Omic Atlas of MASH, Linking Liver Pathway Biology to cfDNA Methylation in Blood [Yahoo! Finance]

Akero Therapeutics, Inc. (AKRO) 
Last akero therapeutics, inc. earnings: 3/16 07:30 am Check Earnings Report
Company Research Source: Yahoo! Finance
FOSTER CITY, Calif., November 10, 2025 BUSINESS WIRE Hepta , a biotechnology company using transformer-based AI to decode the cell-free DNA (cfDNA) epigenome and detect organ-specific signals of chronic disease, today announced the creation of an unparalleled multi-omic atlas of metabolic dysfunction–associated steatohepatitis (MASH) in collaboration with Duke University. This work builds on Hepta's expanded cfDNA studies with Mainz University and Akero Therapeutics' Phase 3 clinical trial program, further strengthening the company's partnerships across academic and clinical research. The atlas integrates single-cell and bulk data across hundreds of liver samples, including gene expression, chromatin accessibility, and DNA methylation, paired with cfDNA methylation from matched blood plasma. Presented this week at AASLD's The Liver Meeting , the atlas reveals how coordinated methylation and transcriptional programs drive inflammation and fibrosis and demonstrates that these same mo Show less Read more
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