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Stock impact report

Annexon Offers A High-Risk, High-Reward Play On A New Approach To Complement-Mediated Diseases [Seeking Alpha]

Annexon, Inc. - common stock (ANNX) 
Company Research Source: Seeking Alpha
Tanruprubart's Phase III results are promising, but there is U.S. regulatory uncertainty due to non-U.S. trial sites and dose-response questions. Vonaprument's Phase III trial focuses on vision preservation, potentially differentiating ANNX in the competitive but large geographic atrophy market. I estimate fair value at $14.50/share, with 2026 as a pivotal year for clarity on the tanruprubart filing process, clinical vonaprument milestones, and possible commercial partnerships. jtamm/iStock via Getty Images Although systemic complement-mediated diseases are, fortunately, relatively rare, there is a wider range of diseases where complement overactivation plays a significant role, and these are often hard-to-treat diseases with serious quality of life implications. Annexon ( This article was written by Analyst's Disclosure: I/we have no stock, option or similar derivative position in any of the companies mentioned, and no plans to initiate any such positions within the next Show less Read more
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