Hoth Therapeutics Commences Next Phase of VNLG-152 Study
Hoth Therapeutics, Inc. (HOTH)
Company Research
Source: PR Newswire
NEW YORK, April 9, 2020 /PRNewswire/ -- Hoth Therapeutics, Inc. (NASDAQ: HOTH), a biopharmaceutical company, today announced initiating the next phase of its study of VNLG-152 novel retinamides (Retinoic acid metabolism blocking agents or RAMBAs) for the treatment of dermatological diseases, at Weill Cornell Medicine. Hoth continues to examine the efficacy of RAMBAs in blocking acne pathogenic gene expression and carcinogenesis in mice. Solubility and formulation had been established for the drug for use in both human keratinocytes and mouse studies. A human keratinocyte in vitro acne study has been optimized, which uses molecules released by Propionibacterium acnes, or P. acnes, to induce an inflammatory response in these cells. As part of the next phase of this study, the assay will be tested to explore whether VNLG-152 is capable of blocking this inflammatory response. Immediately after identifying an effective dose of VNLG-152, the researchers will conduct studies on mouse skin
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HOTH
News
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- Hoth Therapeutics Issues Comprehensive Pipeline Update Highlighting Clinical Progress, Orphan-Designated HT-KIT, Advancing HT-001 Phase 2, and New GDNF Metabolic ProgramPR Newswire
- Hoth Therapeutics to Present at Noble Capital Markets 21st Annual Emerging Growth Equity Conference, December 2-3, 2025 [Yahoo! Finance]Yahoo! Finance
- Hoth Therapeutics to Present at Noble Capital Markets 21st Annual Emerging Growth Equity Conference, December 2-3, 2025PR Newswire
- Hoth Therapeutics Accepted Into NVIDIA Connect Program, Expanding Its AI and Accelerated Computing Capabilities [Yahoo! Finance]Yahoo! Finance
HOTH
Sec Filings
- 12/5/25 - Form EFFECT
- 11/17/25 - Form S-3
- 11/13/25 - Form 424B5
- HOTH's page on the SEC website