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-0.000204764179919467 -0.00054603781311845 0.00109207562623729 0.000819056719677869 0.000494846768138826 0.000614292539758402 0.00215002388915431 0.000750801993038111
Stock impact report

Novartis to acquire SNV4818 from Synnovation [Yahoo! Finance]

Novartis AG (NVS) 
Last novartis ag earnings: 4/28 01:00 am Check Earnings Report
US:NYSE Investor Relations: novartis.com/investors
Company Research Source: Yahoo! Finance
Under the contract, Novartis will pay $2bn upfront and up to $1bn in milestones to acquire Synnovation Therapeutics' wholly owned subsidiary Pikavation Therapeutics, which holds SNV4818 and related programmes. Through the acquisition, Novartis plans to explore a new method to treat patients with hormone receptor-positive (HR+) / human epidermal growth factor receptor 2 (HER2)- breast cancer and other solid tumour indications. SNV4818 is an oral drug and is presently being assessed in an ongoing Phase I/II trial for breast cancer and other advanced solid tumours. The programme aligns with Novartis' aim to develop treatments for breast cancer and complements existing cyclin-dependent kinase (CDK) inhibitors and endocrine therapies as part of potential combination strategies. Preclinical data has demonstrated strong activity against common Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutations. Clinical evaluation is progressing. The deal is Show less Read more
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