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3.4079678287806E-05 -0.000408956139454059 -0.000439627849913162 0.000579354530893283 0.0013631871315134 -0.000715673244044507 -0.00446443785570665 -0.00725897147530926
Stock impact report

Novartis to buy experimental breast cancer drug in up to $3 billion deal [Yahoo! Finance]

Novartis AG (NVS) 
Last novartis ag earnings: 4/28 01:00 am Check Earnings Report
US:NYSE Investor Relations: novartis.com/investors
Company Research Source: Yahoo! Finance
firm ?Synnovation Therapeutics, adding a targeted therapy to its pipeline of cancer drugs. The ?company will pay $2 billion upfront and up to $1 billion that is contingent on further development achievements as part of the deal. The experimental drug, SNV4818, belongs to a class of selective ?PI3Ka inhibitors, a new ?approach for the treatment of a type of breast cancer known as HR positive/HER2 negative ?and potentially other solid tumours. The acquisition adds to a growing pipeline of targeted cancer therapies, including a radioligand therapy candidate, ?that Novartis ?is already testing. SNV4818 ?is currently in early-stage trials ?and has shown promising activity against tumors in lab studies, Novartis said. Synnovation's drug targets only the mutated form of PI3Ka, an enzyme that often malfunctions in breast and other forms of cancer, while sparing the normal version found ?in healthy cells. And it aims ?to avoid the side effects seen ?with existing PI3Ka-inhibiting ?ther Show less Read more
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