Cell and gene therapy companies trip at scalability hurdle [Yahoo! Finance]
Novartis AG (NVS)
Last novartis ag earnings: 4/28 01:00 am
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Source: Yahoo! Finance
One common factor faced by several of these companies is manufacturing challenges and a failure at scaling up. The FDA approved the first autologous dendritic cell therapy, Dendreon Pharmaceuticals's Provenge (sipuleucel-T), in 2010. Since then, major strides have been made in the cell therapy space. The first chimeric antigen receptor (CAR)-T cell therapy, Novartis' Kymriah (tisagenlecleucel), was approved in 2017, which also doubled as the first approval for a gene therapy in the US, and several other countries. Yaky Yanay, the CEO of the Israeli cell-based product company Pluri, says the cell and gene therapy field has rapidly evolved in recent decades. “Understanding what the cells are doing, the mechanism of action, and the secretion has changed the game. Before, we did not have the ability to look closely at cells and to understand the level of complexity and the capabilities of these tiny inadmissible organisms,” says Yanay. GlobalData reports that there are currently 2,0
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NVS
Earnings
- 4/23/24 - Beat
NVS
Sec Filings
- 4/23/24 - Form 6-K
- 2/15/24 - Form S-8
- NVS's page on the SEC website