New Novartis Fabhalta® (iptacopan) data show clinically meaningful and statistically significant proteinuria reduction of 38.3% versus placebo for patients with IgA nephropathy (IgAN) [Yah...
Novartis AG (NVS)
Last novartis ag earnings: 4/28 01:00 am
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Source: Yahoo! Finance
IgAN is a heterogeneous, progressive, rare kidney disease and is a major cause of chronic kidney disease worldwide ; complement activation is a key driver of glomerular inflammation in IgAN There is a need for effective, targeted therapies for IgAN ; up to 30% of patients with persistent proteinuria (=1 g/day) may progress to kidney failure within 10 years, requiring maintenance dialysis and/or kidney transplantation Novartis continues to advance broad renal portfolio in late-stage development, exploring the potential to slow disease progression and extend dialysis-free life Basel, April 15, 2024 – Novartis today presented results from a pre-specified interim analysis of the Phase III APPLAUSE-IgAN study of Fabhalta ® (iptacopan), an investigational Factor B inhibitor of the alternative complement pathway, in patients with IgA nephropathy (IgAN) . In the analysis, patients treated with Fabhalta achieved a 38.3% (p Proteinuria reduction is an increasingly recognized surrogate
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NVS
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- 4/23/24 - Beat
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Sec Filings
- 4/23/24 - Form 6-K
- 2/15/24 - Form S-8
- 2/2/24 - Form SC
- NVS's page on the SEC website