ACTG Announces Publication of STOMP Results in the New England Journal of Medicine [Yahoo! Finance]
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Source: Yahoo! Finance
CHAPEL HILL, N.C., Feb. 25, 2026 (GLOBE NEWSWIRE) -- ACTG, a global clinical trials network focused on HIV and other infectious diseases, today announced the publication of “Tecovirimat for the Treatment of Mpox (STOMP)” in the New England Journal of Medicine (NEJM) . The publication reports on results from STOMP ( S tudy of T ec o virimat for Mp ox, also known as A5418) that demonstrated that tecovirimat did not improve mpox resolution. STOMP stopped enrolling participants in December 2024 after an interim analysis showed that the treatment did not reduce the time to lesion resolution or have an effect on pain among outpatient adults with clade II mpox. “This publication reminds us of the importance of randomized clinical trials – tecovirimat was widely expected by the scientific community to be an effective treatment for mpox and it was only through STOMP that we were able to conclusively demonstrate that it is not,” said ACTG Chair Joseph J. Eron, M.D., University of North Carol
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